While this panel is primarily for screening, the markers it assesses are commonly elevated or indicative in the investigative diagnosis and monitoring of several gastrointestinal and systemic conditions, including:

• Inflammatory Bowel Diseases (IBD): Including Crohn's Disease and Ulcerative Colitis, where markers like C-Reactive Protein (CRP) can indicate active inflammation within the digestive tract. The CBC can reveal anemia or other blood count abnormalities often associated with IBD.
• Celiac Disease (Gluten-Sensitive Enteropathy): The Tissue Transglutaminase (tTG) IgA test is a key serological marker for celiac disease, an autoimmune condition impacting the small intestine. Quantitative IgA is included to assess for IgA deficiency, which can lead to false negative tTG IgA results.
• Gastrointestinal Bleeding: The Fecal Occult Blood test specifically identifies hidden blood in stool, a critical indicator for bleeding anywhere along the gastrointestinal tract, which can be due to polyps, ulcers, diverticulitis, or inflammatory conditions.
• General Gastrointestinal Dysfunction: The Comprehensive Metabolic Panel (CMP) provides broad insights into liver and kidney function, electrolyte balance, and blood sugar, which can be disrupted by chronic digestive disorders or malabsorption.
• Anemia and Nutritional Deficiencies: Both CBC and CMP can highlight anemia or imbalances that might arise from chronic inflammation or impaired nutrient absorption in the gut.