Ferritin
- 82728
What is Ferritin and why is it important?
What is Ferritin and why is it important?
Diagnose hypochromic, microcytic anemias. Decreased in iron deficiency anemia and increased in iron overload. Ferritin levels correlate with and are useful in evaluation of total body storage iron. In hemochromatosis, both ferritin and iron saturation are increased. Ferritin levels in hemochromatosis may be >1000 ng/mL.
When to consider Ferritin?
When to consider Ferritin?
- If you are experiencing persistent fatigue, weakness, pale skin, dizziness, or shortness of breath, which could indicate iron deficiency anemia.
- If you have brittle nails, cold hands and feet, restless legs syndrome, or unexplained hair loss.
- If a doctor suspects iron deficiency or iron overload (hemochromatosis) based on other blood tests or symptoms like joint pain, abdominal pain, or unexplained weight loss.
- If you have a chronic inflammatory condition, liver disease, or chronic infection, as these can influence ferritin levels and warrant monitoring.
- If you are pregnant, as iron requirements increase significantly, and monitoring iron stores is important for maternal and fetal health.
As part of a routine check-up to assess your body's overall iron storage and prevent potential deficiencies or excesses before symptoms become severe.
Who benefits from Ferritin?
Who benefits from Ferritin?
- Individuals experiencing symptoms of iron deficiency or overload: If you have unexplained fatigue, weakness, pale skin, shortness of breath, or concerns about iron levels, this test can provide valuable insights.
- Those with a family history of iron-related conditions: Especially for hemochromatosis (iron overload), monitoring ferritin levels can be crucial for early detection and management.
- People with chronic health conditions: Certain inflammatory conditions, liver diseases, chronic infections, or autoimmune disorders can affect iron metabolism and ferritin levels, making this test helpful for monitoring.
- Pregnant individuals: While ferritin levels can be affected late in pregnancy, monitoring iron stores is important throughout to address potential deficiencies.
- Individuals with dietary restrictions or specific health concerns: Such as vegetarians, vegans, or those with gastrointestinal conditions that impact nutrient absorption, who may be at higher risk for iron deficiency.
When is theFerritin used ?
When is theFerritin used ?
- Iron Deficiency Anemia: When ferritin levels are low, it strongly indicates a lack of iron in the body, which is a primary cause of this type of anemia, leading to fatigue and weakness.
- Iron Overload (Hemochromatosis): Elevated ferritin levels, especially when significantly high, are a key indicator of iron accumulation in the body, which can damage organs. This is often seen in conditions like hereditary hemochromatosis.
- Anemia of Chronic Disease: In some chronic inflammatory conditions, ferritin levels can be high despite low iron, as ferritin acts as an acute-phase reactant. This helps differentiate it from iron deficiency anemia.
- Inflammatory Conditions: Since ferritin is an acute-phase reactant, its levels can be elevated during active inflammation, infection, liver disease, or autoimmune disorders, providing insight into the body's inflammatory status.
- Liver Disease: Liver damage can lead to elevated ferritin levels, as the liver is a major site of iron storage and inflammation.
- Certain Cancers: Some cancers can cause an increase in ferritin levels, although ferritin is not a specific tumor marker on its own.
Important Considerations
Important Considerations
It's important to note that ferritin is an acute-phase reactant, meaning its levels can be elevated due to inflammation, liver disease, chronic infections, autoimmune disorders, or certain types of cancer, even if iron stores are not high. Pregnancy can also affect ferritin levels. Always discuss your results with a healthcare provider for proper interpretation in the context of your overall health and medical history.