Cortisol, AM

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The Cortisol, AM test measures the level of cortisol in your blood in the morning, when levels are typically at their highest. Cortisol is a crucial hormone produced by the adrenal glands, playing a vital role in the body's response to stress, metabolism, immune function, and maintaining blood pressure. This test helps assess adrenal gland function and detect imbalances that may contribute to various health issues.

Quick facts

Sample type

Serum

Turnaround

2–4 business days

Fasting

No Fasting Required

Doctor’s order included

Licensed physician review and requisition included with every test.

Cortisol, AM

  • Stress & Adrenal Health
  • General Health & Wellness
  • Cpt Codes
    • 82533

    what is Cortisol, AM and why is it important?

    The Cortisol, AM test measures the level of cortisol in your blood in the morning, when levels are typically at their highest. Cortisol is a crucial hormone produced by the adrenal glands, playing a vital role in the body's response to stress, metabolism, immune function, and maintaining blood pressure. This test helps assess adrenal gland function and detect imbalances that may contribute to various health issues.

    When to Consider a Cortisol, AM Test

    • If you are experiencing symptoms such as chronic fatigue, muscle weakness, or unexplained weight gain or loss.
    • If you have difficulty sleeping, increased irritability, anxiety, or depression.
    • When symptoms like high blood pressure, easy bruising, or thin skin are present.
    • If your healthcare provider suspects an adrenal gland disorder, such as Cushing's syndrome (too much cortisol) or Addison's disease (too little cortisol).

    Who Benefits from a Cortisol, AM Test

    • Individuals experiencing persistent or unexplained fatigue, stress, or changes in mood.
    • Anyone with symptoms that might suggest an imbalance in adrenal gland function.
    • People who have conditions like high blood pressure, sleep disturbances, or unusual weight changes.
    • Those seeking to understand their hormonal balance, especially concerning stress response.

    Commonly Used for Diagnosis of

    • Cushing's Syndrome: This condition results from prolonged exposure to high levels of cortisol. A morning cortisol test, often followed by other specific tests, can help identify abnormally elevated cortisol, which can lead to symptoms like weight gain (especially in the face and trunk), high blood pressure, and muscle weakness.
    • Addison's Disease (Primary Adrenal Insufficiency): This occurs when the adrenal glands produce too little cortisol. Low morning cortisol levels can indicate adrenal gland damage, leading to symptoms such as chronic fatigue, muscle weakness, weight loss, and low blood pressure.
    • Secondary Adrenal Insufficiency: Caused by a problem with the pituitary gland, which regulates adrenal function. A morning cortisol test can help differentiate between primary and secondary adrenal issues when interpreted with other hormone levels.
    • Adrenal Tumors: Both benign and malignant tumors of the adrenal glands can affect cortisol production, leading to either excessive or deficient levels.
    • Hypothalamic-Pituitary-Adrenal (HPA) Axis Dysfunction: This test is crucial for assessing the body's central stress response system, providing insights into how the brain, pituitary gland, and adrenal glands communicate to manage cortisol production.
    • Unexplained Chronic Fatigue or Stress: While not a direct diagnosis, abnormal morning cortisol levels can point towards underlying hormonal imbalances contributing to persistent fatigue, mood disturbances, and difficulty coping with stress.

    Caution

    It's important to discuss your test results with a healthcare provider, who can interpret them in the context of your overall health, symptoms, and medical history. This test is for informational purposes and does not replace professional medical advice, diagnosis, or treatment.

    How It Works?

    1
    Add Your Test to Cart and Check out

    once Test Order is received, Our physicians will review your request and email you the easy-to-follow requisition form.


    2
    Locate and Visit Your Nearest Laboratory

    Find the closest partner location—most are within 2–3 miles—and drop by for a quick, no‑appointment blood draw.


    3
    Get your Results Online

    Once your sample is processed, we’ll send your report straight to your inbox within 1–3 business days. Just click the link to view your results anytime.


    4
    Book a Optional Consult

    Have Questions about results? Book a phone or video visit with one of our doctors. They’ll walk you through your report, explain any findings, and recommend next steps