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UberTests

Type 1 Diabetes Autoimmune Panel

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Diabetes autoantibodies assessment is helpful in identifying and managing patients at risk for development of type 1 diabetes. Published positivity rates for diabetes autoantibodies in new-onset type 1 diabetes patients listed below are based on the combined analysis of GAD-65, ICA 512, insulin antibodies, and ZnT8 antibodies. The combined analysis has a 98% autoimmunity detection rate, with 1.8% diabetic individuals remaining as autoantibody-negative. Fewer than 3% of type 2 diabetics have positive antibodies. Positive rate in new-onset type 1 diabetes patients: GAD-65 antibodies = 68% positive, ICA 512 antibodies = 72% positive, Insulin antibodies = 55% positive, ZnT8 antibodies = 63% positive. An increase in the number of positive antibodies is associated with a higher likelihood of type 1 diabetes.

Quick facts

Sample type

Serum, frozen

Turnaround

2–4 business days

Fasting

No Fasting Required

Doctor’s order included

Licensed physician review and requisition included with every test.

Type 1 Diabetes Autoimmune Panel

  • Diabetes & Blood Sugar
  • Autoimmune Disorders
    • Cpt Codes
    • 86337(x1)
    • 86341(x3)

    what is Type 1 Diabetes Autoimmune Panel and why is it important?

    Diabetes autoantibodies assessment is helpful in identifying and managing patients at risk for development of type 1 diabetes. Published positivity rates for diabetes autoantibodies in new-onset type 1 diabetes patients listed below are based on the combined analysis of GAD-65, ICA 512, insulin antibodies, and ZnT8 antibodies. The combined analysis has a 98% autoimmunity detection rate, with 1.8% diabetic individuals remaining as autoantibody-negative. Fewer than 3% of type 2 diabetics have positive antibodies. Positive rate in new-onset type 1 diabetes patients: GAD-65 antibodies = 68% positive, ICA 512 antibodies = 72% positive, Insulin antibodies = 55% positive, ZnT8 antibodies = 63% positive. An increase in the number of positive antibodies is associated with a higher likelihood of type 1 diabetes.
    • If you are experiencing classic symptoms of diabetes, such as increased thirst, frequent urination, unexplained weight loss, blurred vision, or extreme fatigue, particularly if these symptoms develop quickly.
    • When your healthcare provider needs to determine if your diabetes is caused by an autoimmune process, which is characteristic of Type 1 Diabetes, guiding appropriate treatment and management strategies.
    • If there's a family history of Type 1 Diabetes and a desire to understand personal risk or screen for pre-symptomatic autoimmune activity.
    • Individuals with a family history of Type 1 Diabetes: If you have a close relative with Type 1 Diabetes, this test can help assess your personal risk and provide insights into your genetic predisposition.
    • Individuals with new-onset diabetes: This test is particularly useful for distinguishing between Type 1 and other forms of diabetes, such as Type 2, especially when the diagnosis is uncertain.
    • Individuals suspected of having Type 1 Diabetes: Especially those experiencing rapid onset of symptoms or presenting at a younger age, where an autoimmune cause is suspected.

    The Diabetes Autoimmune Profile is a critical diagnostic tool primarily used for:

    • Type 1 Diabetes (T1D): To confirm the autoimmune nature of diabetes, differentiating it from Type 2 Diabetes and other forms, especially in new-onset cases or individuals with atypical presentations.
    • Latent Autoimmune Diabetes in Adults (LADA): This test helps identify adults who may have a slower-onset form of autoimmune diabetes, often initially misdiagnosed as Type 2 Diabetes.
    • Prediabetes with Autoimmune Markers: For individuals with impaired glucose tolerance or prediabetes, detecting these autoantibodies can indicate a higher risk of progression to overt Type 1 Diabetes.
    • Genetic Risk Assessment for Type 1 Diabetes: In those with a family history of Type 1 Diabetes, this panel can assess the presence of autoimmune markers, providing insight into an individual's predisposition to the condition.
    • Pancreatitis-related Diabetes: To rule out autoimmune causes in some cases of diabetes following pancreatic inflammation.

    Caution

    Understanding your test results is an important step in managing your health. It is crucial to discuss the findings of this test with your healthcare provider, who can interpret them in the context of your overall health, symptoms, and medical history, and recommend appropriate next steps and treatment plans.

    Frequently Ordered Together

    How It Works?

    1
    Add Your Test to Cart and Check out

    once Test Order is received, Our physicians will review your request and email you the easy-to-follow requisition form.

    2
    Locate and Visit Your Nearest Laboratory

    Find the closest partner location—most are within 2–3 miles—and drop by for a quick, no‑appointment blood draw.

    3
    Get your Results Online

    Once your sample is processed, we’ll send your report straight to your inbox within 1–3 business days. Just click the link to view your results anytime.

    4
    Book a Optional Consult

    Have Questions about results? Book a phone or video visit with one of our doctors. They’ll walk you through your report, explain any findings, and recommend next steps